Eine Arbeitsgruppe des Instituts für Industriewissenschaften der Universität Tokio hat einen neuen photodynamischen Ansatz zur Krebsbehandlung vorgestellt. Die Ergebnisse der Studie wurden kürzlich in der Fachzeitschrift Chemical Communications vorgestellt. Was sind photodynamische Therapien? Die photodynamische Therapie wird derzeit nur bei äußeren Tumoren angewendet, die nicht mehr als drei Millimeter in die Haut eingedrungen sind. Die Behandlung gilt als relativ mild, da gesundes Gewebe weitgehend unbeeinflusst bleibt. Saures Milieu hemmt die Wirksamkeit Bei einer Anwendung gegen innere Tumore standen Forscherteams bisher jedoch vor unüberwindbaren Hürden, weil die potenziellen Wirkstoffe durch gewebedurchdringendes Rotlicht aktiviert werden müssen und auch in der sauerstoffarmen Umgebung wirken, die normalerweise in Tumoren herrscht....

Ajax Amsterdam, Barcelone, Juventus… Monaco pourrait s’offrir une affiche de gala, dans un peu plus de trois mois, au C3. Qualifiée pour le tour suivant, l’équipe de la Principauté n’a pas manqué l’occasion de poursuivre son aventure européenne, devant son public du Louis II, où ce sont les supporters serbes qui ont été les plus bruyants tout au long de la soirée. Sur le terrain, cependant, leur équipe n’existait pas initialement en première période....

In a letter sent on Tuesday, Sir Robert Goodwill told Thérèse Coffey, the environment secretary, that his committee had heard evidence that repeated mass deaths had a “profound and long-lasting effect … on fishing communities”. He called for the urgent appointment of an independent panel of experts to investigate the causes of the deaths. Until the impact of the dredging is ascertained, large-scale dredging in the area should be avoided, Goodwill said, and “maintenance dredging should be kept to the minimum level necessary to keep the port operational until the team’s investigation is complete....

Das Solardachpaneel ist widerstandsfähig gegen Hagel und Sturm, sagt Fabian Klaus, Anwendungstechniker bei PREFA. „Das Produkt ist voll abgestützt, sodass auch ein Handwerker darauf laufen kann.“ Das Ziel ist vor allem, optisch zu überzeugen – und damit diejenigen anzulocken, die keine Photovoltaik-Elemente mögen oder keinen eigenen Aufbau auf dem eigenen Dach wollen. Die große Variante hat eine maximale Leistung von 100 Watt. Herkömmliche Solarmodule haben je nach Material und Größe eine maximale Leistung zwischen 50 und 350 Watt....

A US Navy aircraft carrier strike group is moving in waters off the Korean Peninsula as tensions flare after a series of North Korean missile launches over the past two weeks, South Korean security officials said. South Korea’s National Security Council (NSC) held an emergency meeting on Thursday after North Korea launched two more short-range ballistic missiles, the sixth such launch in 12 days, the country’s presidential office said in a statement....

Italy’s new right-wing government has remained silent on rescue groups’ repeated requests for safe harbor, effectively blocking three charity ships – the Norwegian-flagged Ocean Viking and Geo Barents and the German-flagged Humanity 1 – at sea for more than a week. Rome last week sent letters to the embassies of Norway and Germany, saying NGO ships flying their flags were not following European security rules and undermining what it described as a fight against irregular migration....

The NUS said Dalali was removed from the presidency this week after an independent investigation into the allegations found “significant breaches of NUS policies” – but that it would not disclose further details due to employee confidentiality. A statement from Carter-Ruck lawyers on behalf of Dallali said it was “examining all available legal avenues” to challenge her dismissal. The statement said the NUS move followed a disciplinary panel hearing in late October....

The Canadian Union of Public Employees (CUPE) said workers will walk off the job Friday and beyond, despite legislation that would make a strike illegal. Educators, educational assistants and preschool guardians are participating in the strike action. The Ontario Public Service Employees Union (OPSEU) announced today that 8,000 education workers will also walk out on Friday in solidarity with their CUPE counterparts. Their largest group of members are in Peel District School Board and York District School Board, both of which have already said the CUPE strike will close schools....

But federal health minister Jean-Yves Duclos says jurisdictions must commit to expanding the use of common core health indicators and creating a “world-class” health data system for the country. Duclos made the remarks shortly before the ministers held a press conference in Vancouver, presenting their proposals to increase health transfers in Canada. Host Minister Adrian Dix says the provinces and territories had reached a “unified and shared approach” in Duclos that health transfers should increase to 35%, a level that should be maintained....

Dans son scénario « pessimiste », Ottawa prédit que le Canada entrera dans une « légère récession au premier trimestre de 2023 », indique le document de seulement 100 pages. “Il est important d’être honnête avec les Canadiens”, a déclaré la ministre des Finances, Chrystia Freeland, lors d’une conférence de presse. La réalité est que l’économie mondiale ralentit et qu’il y a beaucoup d’incertitude. » Cette prévision montre que le taux de chômage culminera à 6,9 % et que la croissance du PIB tombera en territoire négatif (-0,9 %) l’an prochain....

En France, derrière le slogan #BalanceTonPorc, la journaliste Sandra Muller témoigne du harcèlement sexuel qu’elle a subi au travail. Dans son sillage, d’autres victimes dénoncent des acteurs, journalistes, sportifs, hommes politiques, artistes, écrivains… La France avait déjà connu, en 2016, le cas de Denis Baupin, député écologiste accusé de harcèlement et d’agressions sexuelles, et en juin 2017, l’affaire Gérard Darmanin, alors que le ministre faisait l’objet d’une plainte pour viol....

The additional military, ground and air capabilities come as Ukrainian forces press forward in an offensive to retake the southern city of Kherson, even as they face increased airstrikes from Russia, including Iranian-supplied drones. Ukrainian President Volodymyr Zelensky had asked NATO to supply tanks within the first weeks of Russia’s invasion, which began on February 24. On Friday, he tweeted that Ukraine is “grateful [President Biden] and its people [the United States] for another $400 military aid package....

Beaucoup de questions, peu de réponses. Dans l’affaire des respirateurs Philips contre l’apnée du sommeil, soupçonnés de provoquer des cancers, l’Agence nationale du médicament organisait mercredi des auditions publiques retransmises en direct. Matthieu était devant son ordinateur pendant plusieurs heures. Il a pu regarder et écouter des toxicologues et des épidémiologistes répondre aux questions dans ce dossier Philips. Matthieu, c’est ce patient de 45 ans qui nous avait alerté à l’adresse [email protected] sur cette affaire....

The party’s legal adviser, Arthur Hamilton, has been replaced by Michael Wilson, a Poilievre ally and partner at law firm Goodmans, sources said. The sources were not authorized to speak publicly about the change. It is the latest in a series of appointments by Poilievre that includes an overhaul of the party’s powerful fundraising arm and a reported change in a senior leadership role. Wilson, a partner in the litigation group at Goodmans, helped with Poilievre’s leadership campaign....

This article contains graphic content that may not be suitable for some readers. On Wednesday, PRP said in a press release that the suspect, 26-year-old Charanjeet Singh, of Mississauga, was “the victim’s husband for three years.” 22-year-old Chandanpreet Kaur, now identified as the suspect’s wife, was pronounced dead at the scene. Singh was arrested at the scene and taken to a trauma center, where his injuries were treated and deemed non-life-threatening....

“Gentlemen, we interfered, we are intervening and we will intervene,” Prigozhin, who has been accused of running a “troll factory” to influence the outcome of votes in several Western countries, said in a statement cited by his team. “Carefully, precisely, surgically and the way we do it, as we can,” quipped Prigozhin. Prigozhin, 61, was responding to a request for comment on a Bloomberg report that said Russia was meddling in the US midterm elections....