There’s no one-size-fits-all answer to this question, as the best way to stop spam DM’s on Instagram will vary depending on your account and situation. However, some tips on how to stop spam DM’s on Instagram include using filters or other features to reduce the number of messages you receive, using a spam blocker such as Spamhaus or a third-party service like Inbox Zero, and using an AI filter that monitors your account for spam messages.